افتح القائمة الرئيسية
الصفحة الرئيسية
عشوائي
دخول
الإعدادات
عن المعرفة
عدم مسؤولية
المعرفة
بحث
قالب
:
PBB/51738
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عدل
<
قالب:PBB
قبل برو الببتيد جريلين/أوبيستاتين
البنى المتاحة
1P7X
المحددات
الرمزs
GHRL
; MTLRP
المحددات الخارجية
OMIM:
605353
MGI
:
1930008
هومولوجين
:
9487
GeneCards
:
GHRL Gene
طبيعة الجين
الوظيفة الجزيئية
•
G-protein coupled receptor binding
•
growth hormone-releasing hormone activity
•
protein tyrosine kinase activator activity
•
ghrelin receptor binding
المكون الخلوي
•
extracellular region
•
extracellular space
•
endoplasmic reticulum lumen
•
axon
•
secretory granule lumen
العملية الحيوية
•
activation of MAPK activity
•
gastric acid secretion
•
negative regulation of endothelial cell proliferation
•
glucose metabolic process
•
G-protein coupled receptor signaling pathway
•
elevation of cytosolic calcium ion concentration
•
actin polymerization or depolymerization
•
adult feeding behavior
•
response to hormone stimulus
•
hormone-mediated signaling pathway
•
dendrite development
•
negative regulation of angiogenesis
•
growth hormone secretion
•
positive regulation of insulin secretion
•
positive regulation of appetite
•
negative regulation of interleukin-1 beta production
•
negative regulation of locomotion
•
positive regulation of multicellular organism growth
•
regulation of cell proliferation
•
negative regulation of circadian sleep/wake cycle, REM sleep
•
negative regulation of tumor necrosis factor biosynthetic process
•
negative regulation of apoptotic process
•
cortisol secretion
•
response to estrogen stimulus
•
cellular protein metabolic process
•
negative regulation of interleukin-6 biosynthetic process
•
positive regulation of circadian sleep/wake cycle, non-REM sleep
•
negative regulation of insulin secretion
•
decidualization
•
negative regulation of inflammatory response
•
cartilage development
•
positive regulation of corticotropin secretion
•
positive regulation of cortisol secretion
•
positive regulation of synapse assembly
•
regulation of excitatory postsynaptic membrane potential
•
positive regulation of growth hormone secretion
•
positive regulation of growth hormone receptor signaling pathway
•
positive regulation of protein tyrosine kinase activity
الكروموسومات المتناددة Orthologs
النوع
بشري
فأري
Entrez
51738
58991
Ensembl
ENSG00000157017
ENSMUSG00000064177
UniProt
Q9UBU3
Q9EQX0
RefSeq (mRNA)
NM_001134941
NM_021488
RefSeq (protein)
NP_001128413
NP_067463
الموقع (UCSC)
Chr 3:
10.33 - 10.33 Mb
Chr 6:
113.72 - 113.72 Mb
بحث
PubMed
[1]
[2]